Pharmaceutical companies have a vested interest to go on promoting this $19 billion industry. Hit the problem head on and you won’t have to resort to drugs in the first place. Vitamin C is apparently a natural HMG-CoA reductase inhibitor. I’ve written about the mistaken notion that cholesterol is THE cause of heart disease many times. Statin-associated memory loss: analysis of 60 case reports and review of the literature. in January 2016. We’re often asked in Customer Service why I … Coenzyme Q10 is not a vitamin; it’s a vitamin-like fat-soluble antioxidant produced by the body and found in highest concentrations in the heart and pancreas. • Use a CoQ10 supplement. It’s only commonsense. One of the warnings by FDA is that statins may increase the risk of memory loss and confusion. The reduced energy may slow brain function. But, is there a link between these conditions and the use of statins? However, a recent study in Atherosclerosis suggests that CoQ10 does not improve muscle pain in people taking statins. After being on ReMag and ReMyte for several months her blood pressure had dropped from 180/95 to 110/60. I turn to my friend, Kathleen Barnes who wrote a very interesting blog to answer the question “Is Vitamin C the Same as Ascorbic Acid? Ms. Barnes reminds us that in the midst of cold and flu season “Ascorbic acid is only one of a complex variety of elements that make up the Vitamin C molecule. The Vitamin C Foundation recommends 10,000 mg or more ascorbic acid (Vitamin C) and 300 mg or more of ubiquinone (CoQ10) daily to prevent heart disease. The study is created by eHealthMe based on reports of 8,121 people who have side effects when taking Coq10 from the FDA, and is updated regularly. One of the newer test measures subpopulations of lipoproteins and apolipoproteins (lipoprotein(a) (Lp[a]), apolipoprotein A-I (apo A-I), apolipoprotein B (apo B)), and lipoprotein particle composition of LDL and HDL. drugs can block cholesterol without at the same time blocking such vital biochemicals as CoQ10 and dolichols,” Dr. Graveline says. It’s not called ATP-CoQ10. I haven’t completely joined that camp although I do say that 500mg a day of a food-based Vitamin C Complex and possibly 1-2,000 mg of ascorbic acid when the adrenals are under stress or during cold and flu season are reasonable recommendations. The entire contents of this website are based upon the opinions of Dr. Carolyn Dean, unless otherwise noted. Of course this never happened. If you are experiencing any side effects like memory loss, muscle pain, or mental confusion from the use of statin, contact your doctor immediately. This is all amazingly good news for us.”, OK, back to CoQ10, AKA Ubiquinone. According to Drs. This cycle is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins into adenosine triphosphate (ATP) and carbon dioxide. • Lower intake of sugar, grains, and vegetable oils that are high in omega-6 fat I recently came across an article from the Vitamin C Foundation about CoQ10, statins and their interconnectedness of Vitamin C. The author of this article thinks that CoQ10 deficiency is The Greatest Medical Tragedy of All Time. I feel like I just fell down a tunnel. I was drawn to the paper and Kendrick’s book because of customers sending us reams of cholesterol tests for interpretation (which we don’t do) and recent blogs about more advanced cholesterol testing. However that jumps over the more commonsense approach to make sure the body has the building blocks for making its own CoQ10 at any age instead of some synthetic chemical from a lab. 4 Patients taking atorvastatin 10mg/day (n=49) were given coenzyme Q10 (100mg/day) or placebo and the effect on creatine kinase (the level of which may be raised in some patients with myopathy) was studied. She’s the author of over 35 books including best seller The Magnesium Miracle along with IBS for Dummies, Hormone Balance, Death by Modern Medicine, and 110 Kindle books. According to Dr. Jonny Bowden and Dr. Stephen Sinatra, authors of The Great Cholesterol Myth, the top 5 proven causes of heart disease are: 1. However I can see Dr. Langsjoen’s concern. Some people who take statins experience side effects like muscle aches, nausea, digestive issues, liver and kidney concerns, along with decreased CoQ10 levels. However, I have a different position more along the lines of preventive medicine. And these elements are inseparable, meaning their benefits can only be realized when taken as part of a whole food molecule.”, When I was doing research for my new food-based Vitamin C, I learned from Ms. Barnes that “There is a synergistic effect of the multiple components of Vitamin C, including a number of inseparable co-factors, such as rutin, bio-flavonoids (vitamin p), factor k, factor j, factor p, ascorbinogen, protein chaperones, and various enzymes like tyrosinase, which together in their entirety constitute the whole food complex.”. Because isolates like ascorbic acid are cheaper to produce especially when they are chemically rendered in a lab. We all know that Vitamin C prevents scurvy but you may not know that it was in the early 1700s that “a British doctor discovered that eating citrus fruits cured the scurvy (a Vitamin C deficiency disease) so prevalent among sailors who spent months at sea and got very little fresh food. Cholesterol-lowering drugs and low-fat diets don’t necessarily prevent heart disease. One online practitioner correlates heart disease with autoimmunity. Some users of statins get depressed, very irritable, anxious and suicidal. Kendrick is one of several famous cholesterol experts and researchers whose 2016 BMJ paper is titled, “Lack of an Association or an Inverse Association Between Low-Density-Lipoprotein Cholesterol and Mortality in The Elderly: A Systematic Review.” Dr. Kendrick has been an active critic of cholesterol and statin drugs for many years. This flowering plant is found in areas of India and Southeast Asia, and is often included in recipes to help create a … Nowhere on their website did I find a discussion comparing Vitamin C Complex and Ascorbic acid. Therefore, the aim of the present study was to investigate the possible effects of CoQ10 on cognitive function, learning, and memory in middle-aged healthy and diabetic rats. Pharmacotherapy. Dr. Dean encourages you to make your own health care decisions based upon your own research and in partnership with a qualified health care professional. He stopped Statins on July '04 but has lingering cognitive issues; repetitive questioning, short term memory type. Her last echocardiogram showed a healthy and strong heart with an ejection fraction of 60 percent. CoQ10 supports only one of the eight steps in the Krebs cycle compared to magnesium supporting six. Themes ... Statins decrease the production of CoQ10, a nutrient that’s protective of both the heart and the brain. In the supplement industry I’ve observed that a few positive studies of a nutrient will spur on the creation of a new supplement without an in depth analysis whether a supplement is really needed. Memory loss, dementia, and Alzheimer disease epidemics are on the rise in the United States. According to their website The Vitamin C Foundation “is the world’s best information source on Vitamin C – Ascorbic Acid (C6H8O6). CoQ10 and Statins:You should not take statins without CoQ10. Copyright Dr. Carolyn Dean   -  Designed by Thrive I hope this dissertation helps clear up the question that many customers have about CoQ10 and the role it plays in our health. MYTH 4 You can't eat grapefruit if you take a statin. Statins are notorious for dramatically depleting the body of one of its most valuable resources- CoQ10. He describes the failure of medicine to overcome heart disease. CoQ10 levels have also been found to be lower in people with certain conditions, such as heart disease.CoQ10 is found in meat, fish and whole grains. Of course the whole issue of cholesterol being the “cause” of heart disease is being slowly and quietly set aside by allopathic medicine. It's not known if statins' effect on CoQ10 contributes to their adverse effects. Dr. Carolyn Dean is a medical doctor and naturopath. Scientific studies to determine the effectiveness of coenzyme Q10 in reducing statin-related muscle pain have had mixed results. And magnesium is also an antioxidant and probably more important than CoQ10. Although cholesterol is an important component in the brain where it occurs in high concentrations, it’s also linked with heart disease. CoQ10 may only support one enzyme – HMG CoA Reductase. The more I look into CoQ10, the more I maintain my position that CoQ10 is not a foundational nutrient like magnesium. Learn about magnesium, and much more, by subscribing to my health tips by email. It’s no wonder that Dr. Langsjoen is trying to plug the dam, shut the barn door and fill up the glass of people who have been caught up in allopathic medicine’s failed attempt to treat heart disease. So, in true allopathic fashion, alternative medicine practitioners say that we should give supplemental CoQ10 to everyone as they age. Proof also lies in the fact that Merck published a patent claim in 1990 (#4,933,165), which discusses the addition of CoQ10 to statin drugs, in order to overcome statin induced myopathy. Statins and Memory Loss. The following testimonial gives credence to the above statement. A side effect of statin drugs is muscle problems. We can make CoQ10 but it’s well known that humans cannot make vitamin C. Comparing humans to mammals has led some nutrient researchers to theorize that we should take several thousand milligrams of vitamin C to keep up with our four footed friends. Email your questions to: questions@drcarolyndeanlive.com. No one knows what to do or what to believe any more. You can request to have the small particle low-density lipoprotein (LDL) test carried out. As the title of the article implies, Langsjoen said “We are now in a position to witness the unfolding of the greatest medical tragedy of all time – never before in history has the medical establishment knowingly created a life threatening nutrient deficiency in millions of otherwise healthy people.”. Here is all I was able to find on how CoQ10 supplements are produced – they are fermented from yeast or processed from bacteria or tobacco derivatives. For many decades, in the minds of the public and practitioners, ascorbic acid has been synonymous with Vitamin C and that’s just not the case. Dr. Graveline: For over 25 years we have been using cholesterol lowering doses of statins believing cholesterol to be the cause of atherosclerosis. Every prescription bottle of statin contains this warning. However, when so-called “authorities” tell you that you Must Have or Need to Have this supplement and Can’t Live Without that supplement, they are practicing fear-based medicine, much like allopathic doctors do when they tell you that you Must Take statin drugs. BP meds are: enalapril and atenolol. | Powered by WordPress, Lack of an Association or an Inverse Association Between Low-Density-Lipoprotein Cholesterol and Mortality in The Elderly: A Systematic Review, Magnesium, Endurance Athletes & Atrial Fibrillation, Atrial Fibrillation: The Magnesium Option. The Krebs cycle goes by many names: Citric acid cycle, ATP cycle, the TCA cycle (tricarboxylic acid cycle). Preliminary studies have shown that CoQ10 may slow, but not stop, the progression of Alzheimer's disease. Statins are a group of medications that are used to lower high blood levels … 4. Alone, it may have some mild antibiotic effects, so if you have any kind of bacterial infection, large amounts of cheap ascorbic acid might offer some relief.”, This I didn’t know but counter to most of the alternative medicine community she says that “Taken on a long-term basis, ascorbic acid has been found to cause atherosclerosis (hardening of the arteries), cause the breakdown of collagen in the arteries, kidney stones and more health problems, according to a 2012 study from the Women’s Heart Center at Cedars-Sinai Heart Institute.”, According to Ms. Barnes, ascorbic acid is only one element of the Vitamin C complex. Dear Anon. In fact, she says “All vitamins are extremely complex molecules that contain a large number of factors, some of which science hasn’t even identified. Most psychiatric disorders and nervous system diseases are associated with abnormal neurotransmitter activity in the brain. About cholesterol testing and cholesterol studies, Kendrick is brutally clear in the introduction to his book. I find it surprising that they completely leave magnesium out of the picture. Support the structure and function of your body's basic building blocks with the most bioavailable and effective dietary supplements. Though still controversial, some preliminary evidence suggests that CoQ10 may help to prevent or treat the adverse effects, such as muscle pains and liver problems, of taking statin-type cholesterol drugs. Coenzyme Q10 had no significant effect on either statin tolerance or myalgia. • Deal with stress effectively Low levels of acetylcholine are typically extremely low in patients with Alzheimer’s disease. “My wife had open-heart surgery 2½ years ago due mostly to hypertension and obstruction of the coronary arteries. Statins can cause permanent damage to your major organs and cause many serious conditions like heart failure, diabetes, liver damage, kidney damage, infertility, memory loss and confusion to name a few. After dozens of studies, researchers from the reputable institution have found that low-fat diets could be worse than moderate- or high-fat diets for most people. CoQ10 supplementation may also function as a natural aid in lowering cholesterol and improving heart health. CoQ10 supplements may help relieve muscle pain related to statin use. It may be a necessary supplement for people who continue to take statin drugs, but my modus operandi is to get at the cause of health problems and support the body’s structure and function so they won’t need drugs and they won’t need drugs or supplements for the side effects of drugs. The few adverse effects reported in trials include nausea, lowered blood sugar, and gastrointestinal problems .CoQ10 supplementation may increase the tolerability of some chemotherapeutic treatments .If CoQ10 supplements are taken simultaneously with blood pressure medication, blood pressure may become … We’re often asked in Customer Service why I don’t recommend Coezyme Q10. The obvious point is that if you don’t have enough magnesium to get you to the final steps, taking a CoQ10 supplement is only going to boost a lesser amount of substrate to make a lesser amount of ATP. Statins work by inhibiting an enzyme that's integral to cholesterol production in the body. That’s how Food becomes Energy. Statin Medication Use. It’s actually a fun book to read with lots of tongue-in-cheek Scottish humor even though it’s a very serious topic. The mechanism by which vitamin C lowers cholesterol was only discovered around 1985. Now that researchers see that elevating HDL and dropping LDL doesn’t increase lifespan, they are drilling deeper into the cholesterol myth. Apply those two qualities to any disease and you will naturally get an uptick in health. Talk with your doctor if you suspect memory loss from the use of statins. Her last ultrasound of her carotid artery showed a 30 – 40 percent lessening of calcified occlusions. Statin drugs’ interference with CoQ10, say the scientists, increases oxidative stress in the brain and reduces energy production in brain cells. Magnesium is responsible for 1,000 enzymatic processes and 80% of known metabolic functions. So ReMag along with diet and exercise, helps keep your cholesterol from triggering the ire of your doctor who will try to force you to take a statin drug by “scaring you half to death.”. He is 60, quad bypass age 52, Statins for 8 years. Six of the previous steps require magnesium. 2003;23:871-80. Because coenzyme Q10 plays a role in muscle cell energy production, some researchers have proposed that taking a coenzyme Q10 supplement might reduce the risk of muscle-related side effects. Let's break it down further. It is intended as a sharing of knowledge and information from the research and experience of Dr. Dean. According to Dr. Jerry Avorn, a professor at Harvard Medical School, doctors don’t report between 90% and 99% of serious side effects associated with statin drugs. His numerous research studies can be found in the world’s most prestigious scientific journals according to Life Extension Magazine. The American Heart Association recently released new guidelines that, if followed, could double the number of people using cholesterol-lowering drugs. However, what we may be doing when we consider individual nutrients is to assign them a higher dosage not realizing that when we take a synergistic blend of nutrients, like the Completement Formulas, we don’t require them in high amounts. It was also be… In 2011, she launched RnA ReSet and brought her 50 years of experience into her proprietary, unique formulations that give every individual at any stage of wellness or illness the necessary building blocks for sustained health, vitality and well-being. • Avoid smoking Kendrick’s explanation of the myths surrounding cholesterol and its treatment are still fresh even though the book was written in 2008, and will be new for most people. Qunol has the #1 cardiologist recommended CoQ10 supplement offering both ubiquinone and ubiquinol, as well as turmeric supplements to support healthy inflammation response. He says, “It has reached the point where I feel like shouting, ‘Listen guys, I know you need to ‘publish or perish’, and the more publicity you can achieve the bigger the next research budget, but you’re scaring people half to death. Now go away, grow your beard, and do some proper boring research that no one can understand.’”, Here’s where I should mention the good news that magnesium is a “natural statin” and helps balance the enzyme that makes cholesterol. But after that shocking headline she says wants patients to use steroids because they are the main treatment for autoimmune disease! Evans MA, Golomb BA. When Vitamin C levels are low, cholesterol becomes elevated; and when more vitamin C is consumed, cholesterol levels decline. CoQ10 is likely safe when used by healthy adults at moderate doses. Your cells use CoQ10 for growth and maintenance.Levels of CoQ10 in your body decrease as you age. All too often allopathic and alternative doctors are in the position of closing the barn door long after all the horses have escaped. After all CoQ10 is naturally produced in the body, so why not promote our own production. I’d like to comment on this article because its exaggerated title shocks the reader into thinking that CoQ10 is THE treatment for heart disease – and it’s not. Sinatra and Bowden, the following simple lifestyle recommendations can address the underlying cause of heart disease: • Avoid eating processed foods ( 6 ) Statins decrease the production of CoQ10, a nutrient that’s protective of both the heart and the brain. That’s thirty years ago. Sugar This article that I’m commenting on was written by the Vitamin C Foundation, so naturally they brought in the Vitamin C connection, however they equate ascorbic acid with Vitamin C. I’ll first describe why I think whole food Vitamin C is superior to ascorbic acid. Additional research is needed to confirm this effect. However, drugs that lower cholesterol can lead to memory loss. Coenzyme Q10 (CoQ10) can decrease oxidative stress, hyperglycemia, and inflammatory markers, and improve vascular function. CoQ10 can be taken at the same time as statin medication. There is no doubt that cholesterol-lowering statin drugs like Mevacor, Lipitor, and Crestor are linked to serious memory loss, fuzzy thinking, and learning difficulties. Is Brain Fog a Statin Side Effect. Supplements: CoQ10, Omega 3; B5, 6, 12, Folic acid, cinnamon, Vit C & E. I'm in tears today. Dr. Julian Whitaker on Statins and Memory Loss. So, magnesium, by being responsible for the activity of HMG CoA reductase, is helping CoQ10 activity and it is required for CoQ10 production. Let me excerpt from my blog “The Great Cholesterol Con.” The title is inspired by Dr. Malcolm Kendrick’s book with the same name. High total cholesterol lowers the risk of dementia in the elderly. This enzyme is also involved in the production of CoQ10, so statins reduce blood levels of it as well. (), using the MedWatch drug surveillance system of the FDA, found 60 reports of patients who had memory loss associated with statins.Since then, several other case reports and case series have suggested a potential negative association between statins and cognitive function. Why are nutrients separated from their whole food source? Subscribe to receive FREE health tips from Dr. Carolyn Dean. Inflammation While there arent enough studies to confirm how well it works to do this, it may … • Consume heart-healthy fats like olive oil, avocado, nuts, and coconut oil Provide as much information on cholesterol as you can. What is Turmeric? I have found that we only require a handful of synergistic, well absorbed supplements that provide the building blocks for every cell in the body. Recent studies indicate that low-fat diets don’t make people healthier or thinner. He’s in the front lines and sees the horrors of heart failure. RESOURCES: Along the borders and in the links of my web site you can find my books, writings, and my call-in radio show. Statins block the enzyme responsible for cholesterol production (HMG CoA reductase) whereas magnesium speeds up or slows down the activity of that enzyme to create the right amount of cholesterol in the body. According to Ms. Barnes, “What he also found, which has mostly been ignored until recently, was that ascorbic acid was far more biologically available and active while it was still in the red pepper.”. This is either because they have been influenced by the drug companies or they don’t believe there is a correlation. However, only about 25% of people who are hospitalized due to heart attack have high cholesterol. Such drugs lower the production of CoQ10, a nutrient that shields both the brain and the heart. High vitamin C levels inhibit the same the HMG-CoA Reductase enzyme as statin drugs. Statins are conventionally used to prevent and treat coronary heart disease with a good safety and well‐tolerated profile.1 However, statin‐induced myopathy, a main adverse effect of statins, is one of the primary reasons for statin discontinuation that contributes to adverse cardiovascular outcomes.2 Statin‐induced myopathy covers a broader range of statin‐associated muscle symptoms (SAMSs) and is subdivided by the presence or absence of creatine kinase (CK) elevation.3 Previous studies4 have dem… Approximately, one in every five Americans between the ages of 40 and 75 use statins to prevent heart attack, stroke or heart-related diseases. Free radicals ... cholesterol goes down, but so does CoQ10—by as much as 50 percent in some patients! memory loss, confusion, brain fog, difficulty concentrating, paranoia, disorientation, depression and dementia. Statins are cholesterol-lowering drugs commonly prescribed if someone is diagnosed with high cholesterol. It certainly caught my attention, however, because saturating the body with ReMag to dissolve the excess calcium is the solution. In this article we'll discuss coq10 and statins memory. Turmeric is a root vegetable from the ginger family and the star player in curried dishes and the popular drink, Golden Milk. 5. “The effects of cholesterol on memory are fully documented. Such drugs lower the production of CoQ10, a nutrient that shields both the brain and the heart. I recently came across an article from the Vitamin C Foundation about CoQ10, statins and their interconnectedness of Vitamin C. The author of this article thinks that CoQ10 deficiency is The Greatest Medical Tragedy of All Time. Your brain cells would die without cholesterol. The article says that apparently Merck has known for more than 15 years that statin drugs interfere with CoQ10 biosynthesis, however I found studies as early 1990 exploring the statin, HMG CoA reductase, CoQ10 deficiency question. (The side effect has been known for many years, and many experts encourage statin-takers to use CoQ10 supplements to maintain the body’s supply. This scan measures the calcium build up in atherosclerotic plaque, which directly correlates with heart disease including atrial fibrillation. We won't spam you or sell your information. Low-fat diets can contribute to cognitive decline and memory loss. Your body makes CoQ10 in a 17-step process that requires Vitamin C (coming soon in our Whole C ReSet) the B vitamins, which we have in methylated and food-based form in ReAline, and several minerals, which are in ReMag, ReMyte, and our recommended sea salted drinking water. And this was the case for all four types of statins studied. Inhibit formation of CoQ10. Coenzyme Q10 (CoQ10) is an antioxidant that your body produces naturally. The link between statins and memory loss is controversial. Further on the autoimmunity and heart disease topic – both conditions are associated with inflammation. 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